Picoammeter – An Electronic Signal Detector for Streaming Current Biosensor

Sammanfattning

Biosensors are analytical devices that combine a biological recognition element with a physicochemical transducer to detect specific analytes and convert their presence into measurable electrical signals. Among various biosensing modalities - including electrochemical, optical, thermal, and surface plasmon resonance, the streaming current approach is examined in detail. This method utilizes electrokinetic principles rather than redox reactions, generating an electrical current as fluid flows through charged microchannels, driven by ion movement.This project centers on the development of a low-cost, printed circuit board (PCB)-based picoammeter (pA) for signal acquisition from streaming current biosensors. It also includes a data analysis platform and a user-friendly software interface. The PCB incorporates an analog multiplexer to enable signal capture from four sensor channels, facilitating multiplexed biosensing.Integrating electronics with biosensing technology enhances portability, cost-effectiveness, miniaturization, and ease of use—key attributes for point-of-care (POC) diagnostic applications.Keywords